Supports tissue formation, normal growth and development throughout childhood
• An antioxidant and a factor in the maintenance of good health
• Helps to produce and repair connective tissue
• Aids in the development and maintenance of bones, cartilage, teeth, gums and night vision
• Delicious natural papaya and orange flavour

Children’s Chewable Vitamins provides a combination of vitamins and minerals that help support normal growth and development in children. Niacin, thiamine and biotin provide substrates for energy production in the Krebs cycle, while vitamins B₆ and B₁₂ and folate help convert homocysteine into methionine for protein synthesis.¹ Approximately 50-60% of magnesium is found in bones, where it stimulates bone forming osteoblast activity and helps in the development and maintenance of bones and teeth.² Vitamin D helps absorb and use calcium and phosphorus, which are required for normal bone mineralization.³ Daily supplementation with 400 IU of vitamin D helps support bone growth in young children.⁴ Vitamin C also contributes to the development and maintenance of bones and teeth through its role in collagen synthesis, the primary structural protein found in connective tissue.¹ As collagen is also the main protein involved in wound healing, deficiencies in vitamin C may lead to impaired healing of wounds.5 Vitamin A helps maintain the natural barrier of the skin, stimulates immune cell development, and helps maintain eyesight and night vision.^6-8 Low levels of vitamin A can affect iron metabolism, which is necessary for hemoglobin production and proper red blood cell activity.⁹

References
1. Combs, GF. (2012). The Vitamins (4th ed.). USA: Elsevier.
2. de Baaij, JHF, Hoenderop, JGJ, Bindels, RJM. Physiol Rev. 2015; 95: 1-46.
3. Wranicz, J, Szostak-Wegierek, D. Rocz Panstw Zakl Hig. 2014; 65(3): 179-184.
4. Wagner, CL, Greer, FR. Pediatrics. 2008; 122(5): 1142-1152.
5. Campos, ACL, Groth, AK, Branco, AB. Current Opinion in Clinical Nutrition and Metabolic Care. 2008; 11: 281-288.
6. Mukherjee, S, Date, A, Patravale, V, Korting, HC, Roeder, A, Weindl, G. Clinical Interventions in Aging. 2006; 1(4): 327-348.
7. Ruhl, R. Proceedings of the Nutrition Society. 2007; 66: 458-469.
8. Al Tanoury, Z, Piskunov, A, Rochette-Egly, C. Journal of Lipid Research. 2013; 54: 1761-1775.
9. Oliveira, JM, Michelazzo, FB, Stefanello, J, Rondó, PHC. Nutrition Reviews. 2008; 66(3): 141-147.